In a medium bowl mix all the ingredients for the crab cakes and set aside in the fridge for 20 minutes. Roughly chop the lettuce and slice ½ English cucumber. Take crab meat out of the fridge and form 4 patties, return to the fridge for 10 minutes.
Heat a frying pan with the olive oil over medium. Add 2 patties a time, and cook until each side turns golden brown (about 4 minutes per side)
Warm each D’ italiano herb and garlic hamburger buns, and top with tzatziki sauce, lettuce, cucumbers and crab cake.